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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERO1L All Species: 23.94
Human Site: S145 Identified Species: 32.92
UniProt: Q96HE7 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HE7 NP_055399.1 468 54393 S145 G A V D E S L S E E T Q K A V
Chimpanzee Pan troglodytes XP_509950 468 54427 S145 G A V D E S L S E E T Q K A V
Rhesus Macaque Macaca mulatta XP_001103965 468 54383 S145 G A V D E S L S E E T Q K A V
Dog Lupus familis XP_547813 468 54343 S145 G A V D E S L S E E T Q K A V
Cat Felis silvestris
Mouse Mus musculus Q8R180 464 54066 E141 E R L G A V D E S L S E E T Q
Rat Rattus norvegicus Q8R4A1 464 54000 E141 E R L G A V D E S L S E E T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515503 465 53870 S142 G A V D E S L S E E T Q R A V
Chicken Gallus gallus XP_421473 463 52908 E140 N R L G A V D E S L S K E T Q
Frog Xenopus laevis Q6DD71 465 53720 S143 S A V D E S L S V E T Q E A M
Zebra Danio Brachydanio rerio Q7T3D1 489 56571 L136 L G A V N G S L S D E T R Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3A6 483 55641 S155 S D G E D F D S S L G F L D T
Honey Bee Apis mellifera XP_623933 471 55049 S147 Q Y D D C L Y S A K D H N K E
Nematode Worm Caenorhab. elegans Q7YTU4 478 55136 M140 A G N N I D P M D R T L H D D
Sea Urchin Strong. purpuratus XP_796844 897 101920 A571 E D E D Q L G A L D T T I S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7S7 469 53812 D165 G A V D R T I D N R A F R G W
Baker's Yeast Sacchar. cerevisiae Q03103 563 65014 F145 D S D D E C K F L D Q L C Q T
Red Bread Mold Neurospora crassa Q7SEY9 668 75589 E144 P L Q G K L G E D V G E S C V
Conservation
Percent
Protein Identity: 100 99.5 98.7 96.3 N.A. 91.8 91.4 N.A. 84.6 77.7 70.9 62.1 N.A. 46.1 48.4 41.4 29.3
Protein Similarity: 100 99.5 99.3 97.8 N.A. 95.9 95.7 N.A. 90.1 85.4 83.9 75.4 N.A. 64.1 65.6 60.8 37.6
P-Site Identity: 100 100 100 100 N.A. 0 0 N.A. 93.3 0 73.3 0 N.A. 6.6 13.3 6.6 13.3
P-Site Similarity: 100 100 100 100 N.A. 26.6 26.6 N.A. 100 26.6 86.6 13.3 N.A. 20 20 20 40
Percent
Protein Identity: N.A. N.A. N.A. 37.9 22.5 22.1
Protein Similarity: N.A. N.A. N.A. 55.6 41.2 38
P-Site Identity: N.A. N.A. N.A. 26.6 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 46.6 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 42 6 0 18 0 0 6 6 0 6 0 0 36 6 % A
% Cys: 0 0 0 0 6 6 0 0 0 0 0 0 6 6 0 % C
% Asp: 6 12 12 59 6 6 24 6 12 18 6 0 0 12 6 % D
% Glu: 18 0 6 6 42 0 0 24 30 36 6 18 24 0 6 % E
% Phe: 0 0 0 0 0 6 0 6 0 0 0 12 0 0 0 % F
% Gly: 36 12 6 24 0 6 12 0 0 0 12 0 0 6 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 6 6 0 0 % H
% Ile: 0 0 0 0 6 0 6 0 0 0 0 0 6 0 0 % I
% Lys: 0 0 0 0 6 0 6 0 0 6 0 6 24 6 0 % K
% Leu: 6 6 18 0 0 18 36 6 12 24 0 12 6 0 0 % L
% Met: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 6 % M
% Asn: 6 0 6 6 6 0 0 0 6 0 0 0 6 0 0 % N
% Pro: 6 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % P
% Gln: 6 0 6 0 6 0 0 0 0 0 6 36 0 12 18 % Q
% Arg: 0 18 0 0 6 0 0 0 0 12 0 0 18 0 6 % R
% Ser: 12 6 0 0 0 36 6 48 30 0 18 0 6 6 0 % S
% Thr: 0 0 0 0 0 6 0 0 0 0 48 12 0 18 12 % T
% Val: 0 0 42 6 0 18 0 0 6 6 0 0 0 0 36 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % W
% Tyr: 0 6 0 0 0 0 6 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _